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Regarding pancreatitis, other data have argued that, Switching between GLP-1 agonists may increase the risk of adverse effects, especially if dose titration protocols are not followed. Noteworthy: Other studies have found that semaglutide and tirzepatide may actually decrease the risk of recurrent acute pancreatitis. Above all, if you suspect you may be developing pancreatitis, consult with your doctor right away, who will likely advise you to stop taking the medication