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These investigations have examined the compound's biochemical effects in cultured cells and animal models as part of broader research into NNMT and cellular metabolism Importantly, these findings relate to preclinical research and should not be interpreted as evidence of established clinical efficacy, safety or therapeutic benefit in humans

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No definitive primary receptor for DSIP has been conclusively characterized

The effect of catalpol injection on the behavior, cortical vascular repair and the expression of BrdU, in GFAP and Nestin in rats with focal permanent cerebral ischemia