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In particular, the categorization of patients based on molecular subtypes of -cell dysfunction not only refines our understanding of pathogenic mechanisms but also helps predict the efficacy of targeted interventions, including microbiome-modulating approaches and therapy with GLP1R agonists

Table 1 provides an overview of key pharmacological features of the main pharmacological classes used in T2DM, including a summary of clinical data on the potential beneficial effect on depression/depressive symptoms

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