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References [1] Mayo Clinic, Semaglutide (subcutaneous route), September 2025 updated

Previous research Lutein is recognized for its blue light filtering and antioxidant properties, most notably in the retina

Bias and Study Quality Assessment The methodological rigour of the studies included in this meta-analysis was assessed using the Cochrane ROB-2 tool for RCTs and the NewcastleOttawa Scale for observational studies, ensuring comprehensive evaluation of potential bias across all domains