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However, some employer- or insurer-specific plans have chosen to continue covering it so coverage is now highly individualized and may vary based on your specific benefits package

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A 2025 study evaluating the short-term management of obesity found that subcutaneous Tirzepatide was cost-effective compared to both subcutaneous and oral semaglutide, with an incremental cost-effectiveness ratio (ICER) of $34,212 per quality-adjusted life-year (QALY) gained versus oral semaglutide, well below the common willingness-to-pay threshold of $150,000/QALY