oral melanotic macule symptoms COM Jan. 2008 Diagnosis Melanotic macules of the tongue

Non-surgical treatments include hormonal therapies such as gonadotropin-releasing hormone analogs (GnRHa), progestins, selective estrogen receptor modulators, dopamine agonists, prostaglandin analogs, and selective progesterone receptor modulators [56,57]

So "does it work" in the pharmaceutical sense isn't the right frame

All patients were in a stable phase of illness, defined as a change of no more than 10 points in their Social and Occupational Functioning Assessment Scale (SOFAS) score (defined in DSM-IV [44]) between assessment 6 weeks prior to and immediately prior to study participation

Many low-quality vendors change their name every six months to escape a bad reputation