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When drugs or toxins enter the liver, they are typically converted into metabolites that can be more easily excreted

The compounds are distinct from established prescription drugs that have gone through rigorous clinical review

Such a setup would precisely delineate the NSC-derived paracrine factors (e.g., BDNF, VEGF [18, 32], TGF-) responsible for suppressing microglial activation and promoting an anti-inflammatory phenotype, independently of in vivo complexities

Methylprednisolone improves lung mechanics and reduces the inflammatory response in pulmonary but not in extrapulmonary mild acute lung injury in mice