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The debilitating fatigue which seems to be the most common symtpom of B12 deficiency may be due to a combination of neurological factors, anaemia, and the role of B12 in the mitochondria

PMID 23539619

This protein has an effect on cellular senescence and apoptosis, and it interacts with other proteins and signaling pathways to regulate gene expression, affecting cellular responses to stress, DNA repair, and cell survival

Biotin Injection Biotin (Vitamin B7) is a water-soluble B vitamin that acts as an essential cofactor for carboxylase enzymes involved in fatty acid synthesis, gluconeogenesis, and amino acid metabolism