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To further analyze whether apoptosis would coexist with necrosis in APAP-induced hepatotoxicity, we detected APAP-induced apoptosis by TUNEL staining and investigated the possible role of Bcl-2 family proteins and caspase-3 under this pathophysiological condition

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Many people with B-12 deficiency report having foggy brain or difficulty concentrating

539 Genetic and pharmacological inhibition of TDO and KMO can increase KYNA, but not the level of neurotoxic product 3-HK, thereby improving the symptoms of neurodegeneration