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[DOI] [PubMed] [Google Scholar] 44.Baiano A., del Nobile M.A

In phase 3 trials, lecanemab and donanemab slowed clinical decline in early Alzheimers by roughly a quarter to a third over eighteen months, with a known risk of amyloid-related brain swelling and small bleeds

HPLC quantification accuracy decreases as purity approaches 100% due to baseline noise, integration limit uncertainty, and co-eluting trace impurities below detection limits