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Advocates like James Lin, a geriatric-medicine specialist and president of the LECOM Institute for Successful Living in Erie, Pa., told the committee that MOTS-C helps address aging by improving key metrics like grip strength, metabolic function and bone loss, a sentiment echoed by several other speakers

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Empirical studies have demonstrated that markers of OS, such as malondialdehyde and protein carbonyls, are elevated in individuals with diabetes and DN, signifying increased lipid peroxidation and protein oxidation (Almogbel et al., 2017)

Stem cells, through their paracrine secretions, could target this peripheral pathology by promoting the survival of spiral ganglion neurons or the regeneration of IHC ribbon synapses, thereby restoring balanced input to the brainstem