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Wh-ereas the three studies finding a significant therapeutic efficacy of the COX-2 inhibitor were based on patients with a short illness period,113114115 the one study with a negative result was conducted with patients with relatively chronic schizophrenia.116 A meta-analysis showed that augmentation of anti-inflammatory drugs to the antipsychotics would be a potential therapeutic options in patients with schizophrenia, although more evidences should be accumulated.117 Several antioxidant treatment approaches have reported that antioxidants are effective for improving psychopathology in schizophrenia

Headache: Commonly observed at higher doses, manifesting as mild pressure, linked to vascular changes

A guide to analysis of mouse energy metabolism

Nonetheless, it is worth noting that the ERM proteins anchor plasma membrane proteins to the actin cytoskeleton and hence can direct their accumulation at specific regions of the cell surface, and also that cell fusion proteins expressed by reoviruses have been found to direct actin filament formation to drive cell fusion 49,50