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Both systolic and diastolic blood pressure decreased in all treatments at 24 weeks

Maina JG, Balkhiyarova Z, Nouwen A, Pupko I, Ulrich A, Boissel M, et al

| Check manufacturer guidance | Never freeze reconstituted solution | | Shelf life | Per lot expiry | 28 days after reconstitution | --- For complete peptide reconstitution guidance including tirzepatide and semaglutide mixing, see our [Peptide Reconstitution Guide](/guides/how-to-reconstitute-peptides-complete-guide) and [Bacteriostatic Water Usage Guide](/guides/bacteriostatic-water-peptide-reconstitution-guide)

This triagonism distinguishes it from existing therapies such as semaglutide and tirzepatide, which focus on single or dual receptor pathways