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The blockbuster weight loss medications that have transformed conversations about obesity and metabolic healthsemaglutide (Ozempic and Wegovy), tirzepatide (Zepbound or Mounjaro), and retatrutide (a newcomer on the block thats not yet FDA approved but highly anticipated for approval next year)are all peptide-based drugs

However, even for patients with a confirmed lack of B12 , the National Institutes of Health recommends 2,000 mcg per day after a course of B12 injections, eventually tapering down to as little as 1,000 mcg per month

The body needs time to adjust to incretin-based therapy, and rushing that adjustment period does not accelerate long-term results

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