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70 As cells use NADPH to reduce cystine to cysteine, the increased cysteine catabolism by CDO implies the increased consumption of NADPH, which will affect other cell metabolic pathways and the antioxidant capacity as well

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To investigate whether the truncated QMP/LX would be recycled as well as the full-length QMP in vivo, we performed a half-life study in transgenic Tg32 mice expressing human FcRn (human FcRn Tg32) (Fig