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In addition, some studies have shown that GLP1R agonists can improve mortality, increase left ventricular ejection fraction, and attenuate the level of brain natriuretic peptide in the patients with type 2 diabetes and HF

Resumiendo, tirzepatida forma parte de la nueva familia de medicamentos contra la obesidad, agonistas todos ellos de alguna hormona gastrointestinal, que en este caso concreto se vuelven ms selectivos

For example, exendrin-4, a GLP-1 agonist, can reduce hypoglycemic effects in the liver [51] and offer neuroprotection in the nervous system through the activation of autophagy to prevent diabetic retinopathy [52]

Many of the pharmacological interventions and experimental strategies, such as gene editing and stem cell therapies, have shown remarkable effects in extending lifespan and reducing age-related decline in animal models (Mitchell et al., 2015)