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When searching for potential biomarkers of disease status, it was determined that individuals with konzo did have a higher incidence of albumin carbamoylation, a post-translational modification likely induced by increased exposure to a toxic byproduct of linamarin degradation, cyanate 29

For individuals with type 2 diabetes , the incretin effect is reduced, though GLP-1 secretion itself may be normal while another incretin hormone (GIP) is more impaired

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Market response: Novo Nordisk shares declined by approximately 15% following the announcement, underscoring how sensitive the obesity market is to comparative efficacy data