When B12 levels are low, the signs can be varied: Anemia: fatigue, weakness, pale skin, and dizziness Fatigue: a deep-seated weariness that doesn't improve with rest Nerve Damage: tingling or numbness in hands and feet, balance problems, and memory loss (seek medical advice promptly) Mood Disturbances: depression, irritability, and personality changes Who Is Most at Risk for B12 Deficiency
Tagliamonte Journal: Frontiers in Immunology Journal ranking: Q1 Key takeaways: Peptide-based cancer vaccines show promise in preclinical studies, but their limited efficacy in clinical trials is due to factors such as specific target antigen identification, limited immunogenicity, and the highly immunosuppressive tumor microenvironment
Microbiota modulate sympathetic neurons via a gut-brain circuit (in Eng)
Their efficacy stems from a multi-targeted mechanism: they ameliorate hepatic steatosis, potently reduce oxidative stress by scavenging ROS and improving redox status, and directly inhibit the activation of the central NF-B inflammatory pathway
