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Weight reduction may improve these conditions by decreasing mechanical stress, reducing upper-airway obstruction or improving metabolic health

Even more troubling: Some companies are selling raw APIs directly to consumers to be reconstituted at home turning a medication to be taken under medical supervision into a do-it-yourself experiment

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A new study from Lilly helps answer that question: among adults with obesity without diabetes, tirzepatide was associated with greater weight loss than semaglutide at six months, along with stronger improvements in several cardiometabolic measures