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Nevertheless, there is widespread agreement that until now no pharmacological options are available to tackle the entire spectrum of clinical manifestations observed in PCOS [21]

According to the researchers, the findings suggest that semaglutide could potentially address both aspects of the condition simultaneously, by improving metabolic health while also supporting reproductive function

Small sample sizes, brief intervention durations, and varied supplementation protocols with regard to dosage, formulation, and combinations are common limitations of clinical trials

Lipid peroxidation occurs when ROS attack polyunsaturated fatty acids in cell membranes, forming MDA and 4-HNE as toxic byproducts