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395 The loss of double-strand repair pathway due to BRCA1 or BRCA2 mutations renders cancer cells more dependent on the PARPs-mediated repair, and more sensitive to PARP inhibition, raising a possibility of a wider application of PARPi in cancer therapy

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NAD(+) intermediates: the biology and therapeutic potential of NMN and NR

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its use outside regulated clinical trials in the UK is unlawful

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