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In sheep, high-dose thiamine supplementation alleviated overnutrition-induced hepatic steatosis by reducing IL-8 expression in leukocytes and hepatic TNF levels, while having little effect on IL-1, MCP-1, or interferon-gamma IFN- (Kalyesubula et al., 2021)

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Neutrophil extracellular traps (NETs), an intricate structure of DNA scaffold, encompassing myeloperoxidase, histones, and elastases - have gained significant attention as a prospective therapeutic target for gouty arthritis, due to their innate antimicrobial and immunomodulatory properties