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The current protocol (CLI 00125 version 8.0) incorporates revisions to improve comprehension and a reduction in the total number of transfused subjects from 600 to 292 subjects following a blinded interim analysis that confirmed the overall incidence of the primary endpoint and the power of the study
The study involved data from 16,827 patients evaluated by neuro-ophthalmologists, and focused on patients with type 2 diabetes or those who were overweight or obese, comparing those prescribed semaglutide to those using non-glucagon-like peptide-1 receptor agonist (GLP-1 RA) medications
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