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[2] Ongoing research comparing various long-acting estrogen esters suggests that estradiol cypionate provides a favorable pharmacodynamic window, but head-to-head trials remain limited and further study could clarify dosing equivalencies in diverse patient populations

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Peripherally, pancytopenia is most often observed, but only 12 of the major cell types (erythrocytes, leukocytes, platelets) may be depressed in some cases

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