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You might feel a brief pinch during the needle insertion, similar to a blood draw

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Retatrutide dosage In phase 2 clinical trials, retatrutide was given in the following doses: 1mg, 2mg or 4mg (starting dose) 1mg, 4mg, 8mg or 12mg per week (maintenance dose) 12mg per week (maximum dose) The dose escalation was similar to other weight loss medications, with the retatrutide dose increasing every 4 weeks

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