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It works at the cellular level, activating an enzyme called AMP-activated protein kinase (AMPK) often referred to as the bodys metabolic master switch. This activation helps regulate how the body uses and stores energy, improving the way cells process glucose and fats

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Tirzepatide has primarily gastrointestinal side effects that typically improve over time and carries no cardiovascular stimulant risks

Pfizer is developing an oral GLP-1 agonist candidate (danuglipron), and reported positive results from a phase 2 study in May