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Mounjaro should be discontinued immediately if pancreatitis is suspected, and patients should not be rechallenged with the medication
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A typical schedule for a patient at the 2.4 mg maintenance dose looks like this: Weeks 1 to 4: reduce to 1.7 mg weekly Weeks 5 to 8: reduce to 1.0 mg weekly Weeks 9 to 12: reduce to 0.5 mg weekly Weeks 13 to 16: reduce to 0.25 mg weekly Week 17: discontinue, or hold at 0.25 mg as a low-dose maintenance strategy if tolerated Patients using Ozempic (semaglutide 0.5 to 2.0 mg) for type 2 diabetes follow a similar reversal of the 0.25 mg to 0.5 mg to 1.0 mg to 2.0 mg escalation ladder
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