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In the context of NASH, a pivotal event in hepatocyte apoptosis involves the activation of apoptosis signal-regulating kinase 1 (ASK1), which induces dysregulation of glucose and lipid metabolism via downstream p38-JNK1 and JNK2 (JNK1/2) pathways, thereby promoting inflammation [116]

After 3-4 h of light onset each mouse received eye drops of 510 l of 1 mM PSVue -550 in the left eye and HBSS in the right eye as control

Specialized BPC-157 Peptide Therapy BPC-157 is a synthetic peptide derived from a protein found naturally in the human stomach