nasal b12 vs injection Cyanocobalamin Spray 500 mcg: Boost & Energy — Mountainside Medical Rhinocobal Nasal Spray 2.3ml: View

An NNMT inhibitor like 5-amino-1MQ could help by stimulating the synthesis of NAD+, a vital cofactor in the electron transport chain

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The dosing regimen varies depending on whether neurological symptoms are present: With neurological involvement: 1 mg intramuscularly on alternate days until no further improvement, then 1 mg every 2 months [3] [4] Without neurological involvement: 1 mg intramuscularly three times a week for 2 weeks, then 1 mg every 2-3 months for maintenance [3] [4] There is some evidence that high-dose oral B12 (1000-2000 micrograms daily) may be effective even in some malabsorption conditions, though UK practice still generally favours intramuscular treatment in these cases

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