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Pharmacological synergistic effects of SGLT2 inhibitors in DKD therapy Monotherapy with metformin, insulin or pioglitazone alone is poorly effective in maintaining long-term glycemic control and renoprotection in a majority of patients with DKD [41]

The results revealed that GLP-1 receptor agonists (particularly semaglutide) afforded a significant risk reduction encompassing 25 different cancer types