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They are, at best, an adjunct one that might offer significant benefit for carefully selected patients under qualified medical supervision

Hu H, Ding J, Zhang S, Li Y, Bai L, Yuan N

Although they differ in pharmacological profiles, ALCAR and KET both modulate aminergic and glutamatergic neurotransmissions and pain and mood

Fragile X Syndrome, another NDD that is characterized by intellectual disability (ID) among other symptoms, has high comorbidity with ASD and is a result of a CGG triplet repeat expansion mutation in the fragile X mental retardation 1 gene ( FMR1 ) that silences the production of its encoded FMRP protein [45, 46]