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3 Oxidative stress Oxidative stress is a disbalance caused by excessive production of prooxidant substances such as ROS and RNS and/or the antioxidant systems working inefficiently ( in vivo primarily by the mitochondrial respiratory chain during aerobic metabolism ( via a reaction between nitric oxide (NO) and superoxide, and nitrosoperoxycarbonate, generated via a reaction between peroxynitrite and carbon dioxide

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Sleep Hygiene Chronic sleep deprivation impairs the skins integrity, weakens its function as a protective barrier, and exacerbates the inflammation of psoriasis (Oyetakin-White 2015

doi: 10.1016/S2213-8587(22)00349-7