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Apart from TRPC channels, a role for ionotropic glutamate receptors for Ca 2+ entry has been suggested: NMDA receptors permeable to Ca 2+ accomplish Ca 2+ homeostasis [102, 103], and also AMPA receptors may be relevant as pharmacological AMPA receptor antagonism blunts Ca 2+ entry into erythrocytes in response to Cl - removal [104]

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Critical cellular homeostases pathways such as autophagy and mitophagy that clear the cell of damaged macromolecules and organelles such as mitochondria and endoplasmic reticula appear less active in people with diabetes, although the mechanism is unknown (66)