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Despite significant progress in characterizing the oral and gut microbiota, the intricate mechanisms by which the oral-gut axis shapes systemic health remain only partially understood

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Such microglial transitions likely involve epigenetic reprogramming induced by MIA, coupled with metabolic adaptations in response to subsequent stress

Glutamine supplementation is a strategy used in situations of intense catabolism, in which there is a decrease in the synthesis and release of glutamine by the skeletal muscle and increased uptake by other organs (kidneys and liver), such as in prolonged and intense exercises, as well as in overtraining syndrome [125, 126]