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(2018), neurodegeneration-associated molecular patterns (NAMPs) was proposed as endogenous danger signals commonly present in various CNS conditions, which are recognized by a battery of specific receptors constitutively expressed on microglia and trigger their transition into DAM (Figure 3, Table 1), whose primary function is to contain and remove the damage

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Induction of C-X-C chemokine receptor type 7 (CXCR7) switches stromal cell-derived factor-1 (SDF-1) signaling and phagocytic activity in macrophages linked to atherosclerosis

Selective inhibition of CYP17 with abiraterone acetate is highly active in the treatment of castration-resistant prostate cancer