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A 2004 study by the University of Alabama found that the red blood cells in male Alzheimers patients showed a significant lack of glutathione

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[4] [6] The direct delivery of ascorbic acid into the bloodstream allows for supraphysiological concentrations, which could have distinct biological effects, such as pro-oxidant activity in the presence of transition metals or selective cytotoxicity against certain malignant cells, although these applications remain under investigation and are not universally accepted as standard of care

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