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Falta de Estudios en Humanos Aunque los resultados en animales son prometedores, hay un gran inconveniente: no hay suficientes estudios clnicos en humanos

2019;26(9):225765.e4

However, when ROS levels rise beyond the capacity of antioxidants, they can damage cellular macromolecules, disrupt normal cell functions, trigger mitochondria to produce pro-apoptotic proteins, and ultimately lead to the apoptosis of central nervous system neurons (Schieber and Chandel, 2014)