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Low-resource regions such as India, East Asia, North Africa and the Middle East contribute to 80 per cent of the global burden of HCV infection4

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1 The GIPR association was specific to tirzepatide, Eli Lilly's dual GLP-1 and GIP receptor agonist sold as Mounjaro and Zepbound, with carriers of that variant found to be 83% more likely to experience vomiting than non-carriers

Among these, withanolides a class of steroidal lactones such as withaferin A and withanone have been most thoroughly investigated for their anti-inflammatory, anticancer, and neuroprotective effects