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Identifying GLP-1 Non-Responders Early in Treatment Early identification of patients who may not respond adequately to GLP-1 receptor agonist therapy represents a critical step in optimizing obesity treatment pathways

Ongoing research continues to refine our understanding of these medications

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"When I talk to patients about weight management, I always bring up these other options as well, because some people don't want to use a needle." Older prescription weight loss pills include: Hydrogel ( Plenity ) Naltrexone-bupropion ( Contrave ) Orlistat ( Xenical ) Phentermine (Adipex, Suprenza) Phentermine topiramate (Qsmyia) While the GLP-1 agonists can produce a weight loss of 10% to 20%, the average weight lost with older medications is lower in the range of 5% to 10% of the starting body weight