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The most common side effects of tirzepatide are gastrointestinal, including nausea (12-24%), diarrhea (12-17%), vomiting (6-10%), constipation (6-11%), and decreased appetite

The figure is biologically attractive and genetically coherent, but no primary-prevention trial has tested whether treating healthy adults to below 0.6 g/L produces better outcomes than current practice

Limitations: It has relatively low sensitivity and is not suitable for samples with strong antibacterial properties

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