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Patients with a history of diabetic retinopathy should be monitored closely, as rapid improvements in glycemic control have been associated with temporary worsening of retinopathy

Convenience : Weekly injections are easy to administer and fit into busy lifestyles

The trial completed in May 2013 showed that 16 of 22 patients finished treatment with clinical remission achieved in 12.5% (2 patients), clinical response and mucosal healing in 50% of patients, significant reduction in mucosal neutrophils and IL-6 levels in responders, and good tolerability with only mild-to-moderate AEs and three discontinuations due to side effects (83)

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