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In the semaglutide group at baseline, nine of ten (90%) participants with pre-existing hypertension were on at least one antihypertensive medication, with six (60%) participants on one antihypertensive medication, three (30%) on two antihypertensive medications and one participant on none

GLP-1 agonists taken once a week typically cause fewer side effects, but no one wants to start with a week of nausea or vomiting

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Therefore, it is not clear whether the weight loss achieved by semaglutide in the STEP trials will be of the same magnitude if these programs are not available to patients