Insufficient levels of glutathione can lead to: Neurodegenerative disease, including Alzheimers diseases and Parkinsons disease Brain fog Low energy Poor digestion Vision problems Decreased emotional and mental health[xviii] Inefficient detoxification of your cells Greater susceptibility to diabetes, heart disease, and cancer Increased free radical damage to cells Inflammatory diseases You become more susceptible to these problems as you age because your bodys ability to produce glutathione decreases
Most considerations of non-animal alternatives for skin irritation/sensitization testing tend to examine a single aspect of the process (e.g., chemical reactivity, epidermal bioavailability, dendritic cell responses)
Journal of Trace Elements in Medicine and Biology
Low SAM, excessive methylation demand, impaired creatine synthesis, reduced glutathione availability and oxidative stress may place additional strain on mitochondria, potentially contributing to fatigue, variable cognitive stamina, sensory sensitivity, poor stress tolerance and slow recovery from illness