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Cardiovascular safety meta-analysis Results from time-to-event analysis of composite MACE-4 and individual components for the composite outcome included 142 participants with at least one MACE-4 (47 participants with cardiovascular deaths, 60 participants with myocardial infarction (MI) events, 30 participants with stroke events and 14 participants with hospitalized unstable angina (HUA)) and are presented in Fig