Aposhian HV, Carter DE, Hoover TD, Hsu CA, Maiorino RM, Stine E
By synthesizing data from clinical trials and reviews, we categorized the most clinically relevant supplements according to their primary effectsglycemic control, lipid regulation, oxidative stress reduction, and hormonal balancewhile also detailing their recommended doses and treatment durations
One potential mechanism is the Nrf2-ARE pathway, which induces a phase 2 detoxification response that promotes disruption of Nrf2-Keap protein interactions, translocation of Nrf2 to the nucleus, and regulation of target gene expression through the ARE, enhancing cellular defense against oxidative damage (Sharma et al., 2010)
It promotes the migration of cells involved in healing to the site of injury, reduces inflammation, and supports the formation of new blood vessels