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It also lowers glutathione levels, increasing oxidative stress and promoting cancer cell growth

& Gentry, K

doi: 10.1038/nrdp.2015.20

While the NIH does not specify a tolerable upper intake level for vitamin B12, a study published in the JAMA Network Open found that high intakes of vitamin B12, such as from daily supplementation of 25 micrograms or higher, increased the risk of bone fracture [3] [4]