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Because IGF-1 is involved in the hearts response to injury, improves contractility, and reduces cardiac fibrosis, it could be used to improve heart function after myocardial infarction
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According to experts recommendations (e.g., American Academy of Neurology), the first-line treatment medications in migraine prevention are: -blockers (propranolol), antiepileptic drugs (topiramate, valproic acid), and antidepressants (amitriptyline)
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