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Each step up is spaced one week apart, not skipped or delayed, to allow your body to adapt and minimize nausea and gastrointestinal side effects

Weight loss clearly improves the response to drugs, not to mention a myriad of obesity- and psoriasis-related comorbidities

These combined effects can significantly impact iron status, even when dietary intake appears adequate

These include: Nausea (very common, may affect more than 1 in 10 people) Diarrhoea (very common) Vomiting (common, may affect up to 1 in 10 people) Constipation and abdominal pain (common) Decreased appetite (very common) These gastrointestinal symptoms typically diminish over time as the body adjusts to the medication