Weight loss of 7-10% of body weight remains the most evidence-based intervention for improving liver health in NAFLD, as emphasised in NICE guidance
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The state of ketosis, induced by low insulin levels, may generally benefit cancer patients, as KBs have been shown to inhibit glycolysis in various tumor cell lines 73, 74 and probably also patients, 75, 76, 77 and tumor cells often lack the enzymes 78, 79, 80, 81 or oxygenation 82 to effectively use ketones for energy production
Furthermore, it appears to increase GLP1R expression (promoting more GLP-1 receptors) and reduce DPP4 expression (maintaining more active GLP-1)