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375 (19), 18341844 (2016) Gerstein, H.C., Colhoun, H.M., Dagenais, G.R., REWIND Investigators, et al.: Dulaglutide and cardiovascular outcomes in type 2 diabetes (REWIND): a double-blind, randomised placebo-controlled trial

10.1016/j.metabol.2010.03.010 56

Bunik V, Kaehne T, Degtyarev D, Shcherbakova T, Reiser G

Bottom line Semaglutide starts working soon after you take it, but noticeable effects like weight loss or better blood sugar control may take weeks to months to appear